Metals in Therapy and Diagnosis
Metals in Therapy and Diagnosis

Oral Presentations

GAMEZ Group

  • Distinct strategies to generate more selective antiproliferative agents, Brissos R. F.; Presa A.; Caubet, A.; Gamez, P., X Reunión Científica de Bioinorgánica (BioBilbao2017) Bilbao (Spain), July 9-12, 2017.

  • Estrategias para reducir la toxicidad asociada al péptido beta-amiloide en la enfermedad de Alzheimer, Ana B. Caballero, Guillem Vázquez, Alba Espargaró, Raimon Sabaté, Ernesto Nicolás and Patrick Gamez, X Reunión Científica de Bioinorgánica (BioBilbao2017) Bilbao (Spain), July 9-12, 2017.

  • Conjugación de péptidos quelantes a nanopartículas de oro para combatir la toxicidad asociada al cobre en la enfermedad de Alzheimer, Guillem Vázquez, Ana B. Caballero, Ernesto Nicolás and Patrick Gamez, X Reunión Científica de Bioinorgánica (BioBilbao2017) Bilbao (Spain), July 9-12, 2017.

  • Photoactivatable platinum drugs through light-driven modification of the ligand, Presa A.; Gamez, P., XXXVI Biennial Meeting of the Spanish Royal Society of Chemistry Sitges (Spain), June 25-29, 2017.

  • Photoswitching the DNA-interacting properties of coordination compounds, Presa A.; Megan A.; Gamez, P., 14th International Symposium on Applied Bioinorganic Chemistry Toulouse (France), June 7-10, 2017.

  • Design of Anti-Alzheimer’s Disease Theranostics: Fluorescent Chelating Peptides, Guillem Vázquez, Ana B. Caballero, Ernesto Nicolás and Patrick Gamez, II Workshop on Chemistry of Group 11 Elements, Barcelona (Spain), January 26-27, 2017.

  • New Switching Coordination Compounds for Potential Photo-Chemotherapeutic Application, Presa A.; Caballero, A. B.; Gamez, P., 13th European Biological Inorganic Chemistry Conference Budapest (Hungary), August 28-September 1, 2016.

  • Peptidic Chelating Agents: Towards the Development of Anti-Alzheimer’s Disease Theranostics, Vázquez G.; Teruel, C.; Caballero, A. B.; Nicolás, E.; Gamez, P. 13th European Biological Inorganic Chemistry Conference Budapest (Hungary), August 28-September 1, 2016.

  • Multifunctional short peptides for the design of anti-Alzheimer therapeutics, Guillem Vázquez, Ana Belén Caballero, Ernesto Nicolàs, Patrick Gamez, 15th Iberian Peptide Meeting Porto (Portugal), February 10-12, 2016.

  • Development of peptide-based compounds as potential anti-Alzheimer agents, Caballero, A. B.; Vázquez, G.; Nicolás, E.; Gamez, P., 6th International Conference on Metals in Genetics, Chemical Biology and Therapeutics Bangalore (India), February 17-20, 2016.

  • Copper-chelating tripeptides: Binding properties and therapeutic potential against Alzheimer's disease, Ana Belén Caballero, Laia Terol, Guillem Vázquez, Ernesto Nicolàs, Patrick Gamez, 7th Franco-Catalan Meeting - 1st HC3A Meeting Toulouse (France), January 26-27, 2016.

  • Tailoring gold nanoparticles as agents against the aggregation and the extracellular accumulation of amyloid peptides, Ana B. Caballero, Alba Espargaró, Guillem Vázquez, Raimon Sabaté and Patrick Gamez, 10th Anniversary of the Institut de Nanociència i Nanotecnologia, Barcelona, Col·legi Oficial de Metges de Barcelona (Spain), January 26, 2017.

  • Modulating the biological properties of platinum(II) complexes through ligand photoswitching, Gamez, P.; Presa, A., 1st International Caparica Christmas Congress on Translational Chemistry Lisbon (Portugal), December 7-10, 2015.

GARCÍA-TOJAL Group

  • Comparative analysis of commercial graphene derivatives as biomolecule immobilization carriers using an industrial enzyme, N. Antón-Millán, J. García-Tojal, S. Cuesta-López, J. A. Tamayo-Ramos, European Materials Research Society (E-MRS) 2017 Fall Meeting, Warsaw (Poland), September 18-21, 2017.
  • Actividad Biológica de dos Complejos Ciclometalados Análogos de Iridio y Rodio, ¿Qué papel juega el centro metálico?, C. Pérez-Arnaiz, N. Busto, I. Echevarría, M. I. Acuña, G. Espino, J. M. Leal, F. Domínguez, B. García, X Reunión Científica de Bioinorgánica (BioBilbao2017) Bilbao (Spain), July 9-12, 2017.
  • A Novel Dual-functional Theranostic Ir(III) Complex: Biological and Imaging Properties, C. Pérez-Arnaiz, N. Busto, I. Echevarría, M. I. Acuña, G. Espino, J. M. Leal, F. Domínguez, B. García, 14th International Symposium on Applied Bioinorganic Chemistry Toulouse (France), June 7-10, 2017.
  • Reacciones de transferencia de oxígeno en dimetilacetamida catalizadas por MoO2Cl2(DMA)2, F. J. Arnáiz García, R. Rubio Presa, M. R. Pedrosa Sáez, R. J. Sanz Diez, M. A. Fernández Rodríguez, 17a Reunión bienal del grupo especializado de Quimica Inorgánica y 11a Reunión bienal delgrupo especializado del estado solido (QIES16) Torremolinos (Spain), June 19-22, 2016.

GIMENO Group

  • Synthesis of Propargyl Functionalised NHC Gold Complexes and Study of their Luminescent and Biological Properties, Alice Johnson, M. Concepción Gimeno, RSC Dalton Younger Members Event, Bath (UK), September 7-8, 2017.
  • Symposium Women in Chemistry, M. Concepción Gimeno, IUPAC 2017 46th World Chemistry Congress, Sao Paulo (Brazil), July 9-14, 2017.
  • Complejos Luminiscentes de oro(I): Citotoxicidad y Biodistribución, Vanesa Fernández-Moreira, Andrés Luengo, Isabel Marzo, M. Concepción Gimeno, X Reunión Científica de Bioinorgánica (BioBilbao), Bilbao (Spain), July 9-12, 2017.
  • Heterometallic Re(I)/Au(I) complexes as theranostic agents, M. Concepción Gimeno, Andrés Luengo and Vanesa Fernández-Moreira, 14th International Symposium on Applied Bioinorganic Chemistry (ISABC14), Toulouse (France), June 7-10, 2017.
  • Hacia el diseño de fármacos para diagnóstico y terapia: Compuestos luminiscentes NHC de Re(I)/Au(I), Andrés Luengo, Vanesa Fernández-Moreira, M. Concepción Gimeno, Isabel Marzo,7ª Jornada de Jóvenes Investigadores en Física y Química de Aragón, Zaragoza (Spain), November 24, 2016.
  • Synthesis of Gold(I) catalysts and study of multicomponent reactions in the formation of indolicines and propargylamines, Mélanie Aliaga-Lavrijsen, M. Dolores Villacampa, M. Concepción Gimeno, 6th Euchems Chemical Congress, Sevilla (Spain), September 11-15, 2016.
  • An efficient and sustainable synthesis of NHC gold complexes, Alice Johnson, M. Concepción Gimeno, XXXIV GEQO Congress Organometallic Chemistry Group, Girona (Spain), September 7-9, 2016.

RUIZ Group

  • Iridium(III) and ruthenium(II) complexes in therapy and phototherapy, J. Ruiz, MetDrugs scientific meeting, Barcelona (Spain), November 30, 2017.
  • Highly potent extranuclear-targeted luminescent iridium(III) antitumor agents containing benzimidazole-based ligands with a handle for functionalization, G. Vigueras, J. G. Yellol, S. A. Perez Henarejos, G. Yellol, J. Zajac, A. Donaire, V. Novohradsky, C. Janiak, V. Brabec, J. Ruiz, II Congreso de jovenes químicos y bioquímicos terapeuticos (II QuimBioQuim2017) Móstoles (Spain), October 4-5, 2017.
  • Exploring the influence of the aromaticity on the anticancer and antivascular activities of organoplatinum(II), A. M. Zamora, S. A. Perez Henarejos, M. Rothemund, V. Rodriguez, R. Schobert, C. Janiak, J. Ruiz, X Reunión científica de bioinorgánica de la asociación española de bioinorganica (BioBilbao) Bilbao (Spain), July 9-12, 2017.
  • Selective "light-switch" of organoplatinum(II) complexes to rich AT B-DNA sequences, A. M. Zamora, S. A. Perez Henarejos, E. Watcher, M. Vera, G. Barone, D. Heidary, V. Rodriguez, C. Janiak, E. C. Glazer, J. Ruiz, 17a Reunión bienal del grupo especializado de Quimica Inorgánica y 11a Reunión bienal delgrupo especializado del estado solido (QIES16) Torremolinos (Spain), June 19-22, 2016.

Poster Presentations

GÓMEZ-QUIROGA Group

  • Interaction studies of new potential antitumor complexes derived from heterocyclic-TSCN with biological targets, Ana I. Matesanz, Eva Jimenez-Faraco, María C. Ruiz, Carmen Navarro-Ranninger, Ignacio E. León, ICBIC 18, Florianopolis (Brazil), August 1-4, 2017.
  • Complejos de Ni(II) y Pd(II) derivados de 4-(N,N-dimetilamino)benzaldehído tiosemicarbazona; M. C. Lorenzo, A. I. Matesanz, A. G.Quiroga, X Reunión Científica de Bioinorgánica, Bilbao (Spain), July 9-12, 2017.
  • Nuevos tiosemicarbazonatos de pd(ii) y pt(ii) bioactivos. citotoxicidad, selectividad y estudios de interacción con ADN y proteínas; A.I. Matesanz, E. Jiménez-Faraco, M.C. Ruiz, I.E. León, C. Navarro-Ranninger, A. Gómez-Quiroga; X Reunión Científica de Bioinorgánica, Bilbao (Spain), July 9-12, 2017.
  • Diseño de complejos metálicos de platino(II) con ligandos PDT; I. Zubieta, A. Presa, P. Gamez, A.G. Quiroga; X Reunión Científica de Bioinorgánica, Bilbao (Spain), July 9-12, 2017.

GARCÍA-TOJAL Group

  • Film-shaped inorganic-organic hybrid polymers with biological properties, E. Cerrada, M. Laguna, H. El Kaoutit, S. Fernández, L. Medinilla, M. Trigo, S. Vallejos, F. García, J. M. García, A. Mendía, X Reunión Científica de Bioinorgánica (BioBilbao2017), Bilbao (Spain), July 9-12, 2017.
  • Iridium(III) Based Complexes Bearing Hydroxyphenylbenzoazole Ligands as Photodynamic Therapy Agents, M. Martínez-Alonso, N. Busto, G. Espino, M. C. Carrión, J. V. Cuevas, A. Carbayo, J. M. Leal, B. García, F. A. Jalón, B. R. Manzano, A. M. Rodríguez, X Reunión Científica de Bioinorgánica (BioBilbao2017) Bilbao (Spain), July 9-12, 2017.
  • Sistemas tiosemicarbazonacobre(II): síntesis, interacción con biomoléculas y estudios biológicos, R. Gil-García, S. Marcos-Gómez, J. Barrera-García, I. Herrán-Torres, G. Madariaga, K. G. Samper, O. Palacios, V. Gómez-Vallejo, J. Llop Roig, R. Alcaraz, C. García-Girón, L. Val-Sanz, P. Muñiz, J. García-Tojal, X Reunión Científica de Bioinorgánica (BioBilbao2017) Bilbao (Spain), July 9-12, 2017.
  • Complejos de paladio(II) conteniendo ligandos tionato funcionalizados altamente solubles en agua, A. Mendía, A. Almássy, J.A. Pérez, L. Medinilla, E. Cerrada, M. Laguna, Reunión Metals and Water 2017, Jaca (Spain), June 13-15, 2017.
  • Iridium(III) complexes bearing new N-Benzyl-N,N-Dipyridylamine ligands: Properties and application in photodynamic therapy, A. Ruiz-Riaguas, M. Vaquero, J. Fidalgo, G. Espino, A. Carbayo, B. García, N. Busto, F.A. Jalón, B. R. Manzano, 14th International Symposium on Applied Bioinorganic Chemistry (ISABC14) Toulouse (France), June 7-10, 2017.
  • Photodynamic Therapy in Iridium(III) Complexes bearing Hydroxyphenylbenzazole Ligands, M. Martínez-Alonso, G. Espino, N. Busto, M.C. Carrión, J. V. Cuevas, A. Carbayo, B. García, F. A. Jalón, B. R. Manzano, A. M. Rodríguez, 14th International Symposium on Applied Bioinorganic Chemistry (ISABC14) Toulouse (France), June 7-10, 2017.
  • Synthesis and characterization of Ir(III) and Rh(III) bis-cyclometalated complexes. Study of their photophysical and cytotoxicity properties, Jairo Fidalgo, Begoña Garcia, José M. Leal, Natalia Busto and Gustavo Espino, 14th International Symposium on Applied Bioinorganic Chemistry (ISABC14) Toulouse (France), June 7-10, 2017.
  • Organoiridium half-sandwich complexes: structure-activity relationship study, Ana R. Rubio, Natalia Busto, Marta Martínez, Gustavo Espino, José María Leal, Begoña García, 14th International Symposium on Applied Bioinorganic Chemistry (ISABC14) Toulouse (France), June 7-10, 2017.
  • Targeting Mitochondrial NAD+/NADH Ratio Using a New Rhodium Compound, M. I. Acuña Pérez, N. Dávila, S. González, M. Martínez, N. Busto, G. Espino, B. García, J. M. Leal, F. Domínguez, EMBO Conference. Translational Research in Cancer Cell Metabolism, Bilbao (Spain), October 4-6, 2016.
  • Iridium-Catalyzed 3O2 Photoexcitation and Photooxidation Reactions, M. Martínez-Alonso, G. Espino, M. C. Carrión, J. V. Cuevas, A. Carbayo, B. García, F. A. Jalón, B. R. Manzano, A. M. Rodríguez, XXXIV GEQO Congress, Organometallic Chemistry Group (GEQO 2016) Girona (Spain), September 7-9, 2016.
  • Ru- Rh- and Ir-based catalytic transfer hydrogenation of quinolines and HCOOH decomposition, J. Fidalgo, J. Valladolid, M. Martínez-Alonso, G. García-Herbosa, A. Carbayo, F. A. Jalón, B. R. Manzano, A. M. Rodríguez, G. Espino, XXXIV GEQO Congress, Organometallic Chemistry Group (GEQO 2016) Girona (Spain), September 7-9, 2016.
  • Anion and ancillary ligand effects on Iridium-based light emitting electrochemical cells, G. Espino, M. Martínez-Alonso, A. Colina, A. Heras, A. M. Rodríguez, A. Pertegás, C. Momblona, J. Cerdá, E. Ortí, H. Bolink, XXXIV GEQO Congress, Organometallic Chemistry Group (GEQO 2016) Girona (Spain), September 7-9, 2016.
  • Experimental and computational evidence for the different modes of binding of Naphtharin, Quinizarin and their respective Ru(II) dinuclear complexes, H. J. Lozano, N. Busto, G. A. Espino, J. M. Leal, B. García,  J. A. Platts, 13th European Biological Inorganic Chemistry Conference Budapest (Hungary), August 28-September 1, 2016.
  • Photoreactivity of newly synthesized cyclometallated complexes: Effect of the metal centre, M. Lari, M. Martínez-Alonso, N. Busto, G. A. Espino, J. M. Leal, B. García, 13th European Biological Inorganic Chemistry Conference Budapest (Hungary), August 28-September 1, 2016.
  • Interaction of an Ir(III) complex with human transferrin, B. Garcia, C. Tiribilly, N. Busto, F. Franzke,  G. Espino, M. Martínez, F. Jalón, B. Manzano, J. M. Leal, 13th European Biological Inorganic Chemistry Conference Budapest (Hungary), August 28-September 1, 2016.
  • The metal centre of organometallic complexes plays an essential role in biological activity, A.R. Rubio, C. Pérez-Arnáiz, N. Busto, H.J. Lozano, M. Martínez, G. Espino, F. Domínguez, M.I. Acuña, J.M. Leal, B. García, 13th European Biological Inorganic Chemistry Conference Budapest (Hungary), August 28-September 1, 2016.
  • Effect of the type of anion on dimer formation of the Ru complex [(η6-p-cymene)Ru(OH2)(κ2-N,N-L1)](TfO)2, J.M. Leal,  J. Santolaya, N. Busto,  G.A. Espino,  M. Martínez,  B. García, 13th European Biological Inorganic Chemistry Conference Budapest (Hungary), August 28-September 1, 2016.
  • Estudio espectroelectroquímico de complejos bisciclometalados de Ir(III) para celdas electroquímicas emisoras de luz (LECs), A. Heras, Á. Colina, G. Espino, M. Martínez-Alonso, XXXVII Reunión del Grupo de Electroquímica (XXXVII GE-RSEQ), Alicante (Spain), July 17-20, 2016.
  • Interaction of Human Serum Albumin (SHA) with an Ir(III) complex, L. Álvarez, N. Busto, C. Tiribilli, J. Santolaya, J. M. Leal, F. Jalón, B. R. Manzano, M. Martínez, G. Espino, B. García, International Symposia on Metal Complexes (ISMEC 2016), Barcelona (Spain), June 7-10, 2016.
  • Rh(III) and Ir(III)-ciclopentadienyl-pyridinyl-quinoline complexes: solution properties and polynucleotides binding, T. Biver, N. Busto, G. Espino, B. García, F. Jalón, G. Luminare, B. Manzano, J. Valladolid, S. Vignali, International Symposia on Metal Complexes (ISMEC 2016), Barcelona (Spain), June 7-10, 2016.
  • Photocleavage and Chemical Properties of Arene-Organometallic Complexes depend of the Metal Center, B. García, N. Busto, M. Lari, A. R. Rubio, C. Pérez, H., J. Lozano, J. M. Leal, M. Martínez, G. Espino, International Symposia on Metal Complexes (ISMEC 2016), Barcelona (Spain), June 7-10, 2016.

GIMENO Group

  • First Synthesis of Group 11 Metal Complexes with α-Hydrazidophosphonate Ligands and Biological Study, R. P. Herrera, D. Salvador-Gil, L. Ortego, M. C. Gimeno, 14th International Symposium on Applied Bioinorganic Chemistry (ISABC14) Toulouse (France), June 7-10, 2017.
  • Síntesis de catalizadores de oro(I) y estudio de las reacciones multicomponentes en la formación de indolizinas y propargilaminas, M. Aliaga Lavrijsen, R. P. Herrera, M. D. Villacampa, M. C. Gimeno, 7ª Jornada de Jóvenes Investigadores en Física y Química de Aragón, Zaragoza (spain) November 24, 2016.
  • Formación de heterociclos de interés biológico con ligandos tio(urea) y estudio de su coordinación a metales, Daniel Salvador Gil, M. Concepción Gimeno, 7ª Jornada de Jóvenes Investigadores en Física y Química de Aragón, Zaragoza (spain) November 24, 2016.
  • An efficient and sustainable synthesis of NHC gold complexes, A. Johnson, M. C. Gimeno, 7ª Jornada de Jóvenes Investigadores en Física y Química de Aragón, Zaragoza (spain) November 24, 2016.
  • Activation and Cyclization Processes in Thioureas, Daniel Salvador Gil, M. Concepción Gimeno, 6th Euchems Chemical Congress, Sevilla (Spain) September 11-15, 2016.
  • Re(I) and Re(I)/Au(I) complexes for cell imaging and therapy applications, A. Luengo, V. Fernández-Moreira, M. C. Gimeno, I. Marzo, 6th Euchems Chemical Congress, Sevilla (Spain) September 11-15, 2016.
  • Alkynyl gold(I) derivatives as selective anticancer drugs, E. Cerrada, C. Sanchez, I. Mármol, P. Castellnou, S. Gascón, M. C. Gimeno, M. J. Rodriguez-Yoldi, XXXIV GEQO Congress Organometallic Chemistry Group, Girona (Spain) September 7-9, 2016.
  • Bioactive amino acid and peptide gold complexes, M. C. Gimeno, A. Gutiérrez, A. Laguna, XXXIV GEQO Congress Organometallic Chemistry Group, Girona (Spain) September 7-9, 2016.

RUIZ Group

  • Highly potent extranuclear-targeted luminescent iridium(III) antitumor agents containing benzimidazole-ligands with a handle for functionalization, G. Vigueras, J. G. Yellol, S. A. Perez Henarejos, G. Yellol, J. Zajac, A. Donaire, V. Novohradsky, C. Janiak, V. Brabec, J. Ruiz, X Reunión Científica de Bioinorgánica (BioBilbao2017) Bilbao (Spain), July 9-12, 2017.
  • Organorutenio complejos con ligandos C'N agentes citotoxicos altamente potentes que actuan con un nuevo mecanismo de accion, J. Kasparkova, J. G. Yellol, H. Stuchlikova, H. Kostrhunova, G. Yellol, V. Novohradsky, D. Bautista, J. Ruiz, V. Brabec, M. D. Santana, X Reunión Científica de Bioinorgánica (BioBilbao2017) Bilbao (Spain), July 9-12, 2017.
  • Synthesis and development of novel metallodrugs based on benzimidazole with therapeutic activity, J. Ruiz, J. G. Yellol, S. A. Perez Henarejos, J. Zajac, G. Vigueras, G. Yellol, V. Novohradsky, V. Brabec, A. Donaire, K. J. Barnham, A. M. Zamora, C. Janiak, A. Grandioso, V. Marchan, 14th International Symposium on Applied Bioinorganic Chemistry (ISABC14) Toulouse (France), June 7-10, 2017.
  • Selective "light-switch" of organoplatinum(II) complexes to rich AT B-DNA sequences, J. Ruiz, Gordon Research Conference on Metals in Medicine (GRC) Andover, New Hampshire (USA), June 26-July 1, 2016.
  • Integrin-targeted delivery of an organoplatinum(II) complex through RGD peptide conjugation, A. M. Zamora Martinez, A. Grandioso, V. Rodriguez Hernandez, J. Ruiz Lopez, V. Marchan, 13th European Biological Inorganic Chemistry Conference (EUROBIC-13) Budapest (Hungary) August 28-September 1, 2016.
  • New acridine thiourea gold(I) complexes as DNA intercalators, anticancer agents and vasculogenic mimicy inhibitors, S. A. Perez Henarejos, M. C. D. Haro, C. Vicente, A. Donaire, A. M. Zamora, G. Vigueras, V. Brabec, D. Bautista, J. Ruiz, 17a Reunion Bienal del Grupo Especializado de Quimica Inorganica y 11a Reunion Bienal del Grupo Especializado de Quimica del Estado Solido (QIES16) Torremolinos (Spain) June 19-22, 2016.

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News

7 March 2017: Conchita Gimeno is one of the awardees of the IUPAC 2017 Distinguished Women in Chemistry

 

20 October 2016: Second MetDrugs meeting

 

2 February 2016: First MetDrugs meeting

 

14 october 2015: The Ministry of Economy and Competitiveness of Spain finances the network

Ref: CTQ2015-70371-REDT

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