Metals in Therapy and Diagnosis
Metals in Therapy and Diagnosis

Papers Published by MetDrugs Members:

  • Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy, Ana Zamora, Gloria Vigueras, Venancio Rodríguez, M. Dolores Santana, José Ruiz Coord. Chem. Rev. 2018, 360, 34-76.
  • Evaluation of the metal-dependent cytotoxic behaviour of coordination compounds, Jordi Grau, Cristina Renau, Ana B. Caballero, Amparo Caubet, Marta Pockaj, Julia Lorenzo, Patrick Gamez Dalton Trans. 2018, 47, accepted for publication.
  • Exploring the Effect of the Polypyridyl Ligands on Anticancer Activity of Phosphorescent Iridium(III) Complexes: From Proteosynthesis Inhibitors to Photodynamic Therapy Agents, Jitka Pracharova, Gloria Vigueras, Vojtech Novohradsky, Natalia Cutillas, Christoph Janiak, Hana Kostrhunova, Jana Kasparkova, José Ruiz, and Viktor Brabec Chem. Eur. J. 2018, 24, accepted for publication.
  • Copper redox chemistry of plant frataxins, Manu Sanchez, Oscar Palacios, Celeste Buchensky, Laura Sabio, Diego Fabian Gomez-Casati, Maria Ayelen Pagani, Merce Capdevila, Silvia Atrian, Jose M. Dominguez-Vera J. Inorg. Biochem. 2018180, 135-140.
  • Drastic effect of the peptide sequence on the copper-binding properties of tripeptides and the electrochemical behaviour of their copper(II) complexes, Silvia Mena, Andrea Mirats, Ana B. Caballero, Gonzalo Guirado, Leoní A. Barrios, Simon J. Teat, Luis Rodriguez-Santiago, Mariona Sodupe and Patrick Gamez Chem. Eur. J. 2018, 24, accepted for publication.
  • Mononuclear Pd(II) and Pt(II) complexes with an α-N-heterocyclic thiosemicarbazone: cytotoxicity, solution behaviour and interaction versus proven models from biological media, Ana I. Matesanz, Eva Jimenez-Faraco, María C. Ruiz, Lucia M. Balsa, Carmen Navarro-Ranninger, Ignacio E. León, Adoracion G. Quiroga Inorg. Chem. Front. 2017, accepted for publication.
  • Revisiting the thiosemicarbazonecopper(II) reaction with glutathione. Activity against colorectal carcinoma cell lines, Javier García-Tojala, Rubén Gil-García, Víctor Ivo Fouz, Gotzon Madariaga, Luis Lezama, María S. Galletero, Joaquín Borrás, Friederike I. Nollmann, Carlos García-Girón, Raquel Alcaraz, Mónica Cavia-Saiz, Pilar Muñiz, Òscar Palacios, Katia G. Samper, Teófilo Rojo J. Inorg. Biochem. 2018, 180, 69-79.
  • Molybdenum-Catalyzed Synthesis of Nitrogenated Polyheterocycles from Nitroarenes and Glycols with Reuse of Waste Reduction Byproduct, Rubén Rubio-Presa, Marı́a R. Pedrosa, Manuel A. Fernández-Rodríguez, Francisco J. Arnáiz, Roberto Sanz Org. Lett. 2017, 19, 5470–5473.
  • Low-toxicity metallosomes for biomedical applications by self-assembly of organometallic metallosurfactants and phospholipids, Maribel Marín-García, Núria Benseny-Cases, Mercedes Camacho, Joan Suades, Ramon Barnadas-Rodríguez Chem. Commun., 2017, 53, 8455-8458.
  • Hybrid aramids, Ir(III)-functionalized aromatic polyamides, Álvaro Miguel-Ortega, Miriam Trigo-López, Félix C. García, José A. Reglero, Marta Martínez-Alonso, Gustavo Espino, José Miguel García Eur. Polym. J. 2017, 95, 119-126.
  • Trackable Metallodrugs Combining Luminescent Re(I) and Bioactive Au(I) Fragments, Andrés Luengo, Vanesa Fernández-Moreira, Isabel Marzo, M. Concepción Gimeno Inorg. Chem. 2017, 56, 15159–15170.
  • Synthesis and Biological Evaluation of Ru(II) and Pt(II) Complexes Bearing Carboxyl Groups as Potential Anticancer Targeted Drugs, M. Ángeles Martínez, M. Pilar Carranza, Anna Massaguer, Lucía Santos, Juan A. Organero, Cristina Aliende, Rafael de Llorens, Iteng Ng-Choi, Lidia Feliu, Marta Planas, Ana M. Rodríguez, Blanca R. Manzano, Gustavo Espino, and Félix A. Jalón Inorg. Chem. 2017, 56, 13679–13696.
  • Interstrand DNA covalent binding of two dinuclear Ru(II) complexes. Influence of the extra ring of the bridging ligand on the DNA interaction and cytotoxic activity, Héctor J. Lozano, Natalia Busto, Gustavo Espino, Arancha Carbayo, José M. Leal, James A. Platts, Begoña García Dalton Trans. 2017, 46, 3611–3622.
  • Highly Stable and Efficient Light-Emitting Electrochemical Cells Based on Cationic Iridium Complexes Bearing Arylazole Ancillary Ligands, Marta Martínez-Alonso, Jesús Cerdá, Cristina Momblona, Antonio Pertegás, José M. Junquera-Hernández, Aránzazu Heras, Ana M. Rodríguez, Gustavo Espino, Henk Bolink, Enrique Ortí Inorg. Chem. 2017, 56, 10298−10310.
  • Organoruthenium Complexes with C^N Ligands are Highly Potent Cytotoxic Agents that Act by a New Mechanism of Action, Vojtech Novohradsky, Jyoti Yellol, Olga Stuchlikova, María Dolores Santana, Hana Kostrhunova, Gorakh Yellol, Jana Kasparkova, Delia Bautista, Jose Ruiz, Viktor Brabec Chem. Eur. J. 2017, 23, 15294-15299.
  • Exploring the Influence of the Aromaticity on the Anticancer and Antivascular Activities of Organoplatinum(II) Complexes, Ana Zamora, Sergio A. Perez, Matthias Rothemund, Venancio Rodriguez, Rainer Schobert, Christoph Janiak, Jose Ruiz, Chem. Eur. J. 2017, 23, 5614-5625.
  • Molybdenum-Catalyzed Deoxygenation of Heteroaromatic N-Oxides and Hydroxides using Pinacol as Reducing Agent, Rubén Rubio-Presa, Manuel A. Fernández-Rodríguez, María R. Pedrosa, Francisco J. Arnáiz, Roberto Sanz Adv. Synth. Catal. 2017, 359, 1752–1757.
  • Effect of the Metal Ion on the Enantioselectivity and Linkage Isomerization of Thiosemicarbazone Helicates, Maria J Romero, Vanesa Suarez, Sandra Fernandez-Farina, Marcelino Mareiro, Emilio Martinez-Nunez, Guillermo Zaragoza, Ana M. Gonzalez-Noya, Rosa Pedrido Chem. Eur. J. 2017, 23, 4884-4892.
  • Bioactive gold and silver complexes with thiophene-conjugated amino acid esters, Helen Goitia, Antonio Laguna, M. Concepción Gimeno Inorg. Chim. Acta 2017, in press.
  • DFT Simulation of Structural and Optical Properties of 9-Aminoacridine Half-Sandwich Ru(II), Rh(III) and Ir(III) Antitumoural Complexes and their Interaction with DNA, José Pedro Cerón-Carrasco, José Ruiz, Consuelo Vicente, Concepción de Haro, Delia Bautista, José Zúñiga, Alberto Requena J. Chem. Theory Comput. 2017, 13, 3898–3910.
  • Photophysical and bioactivity behavior of fac-rhenium(I) derivatives containing ditopic sulfurpyridine ligands, Vanesa Fernández-Moreira, Héctor Sastre-Martín Inorg. Chim. Acta 2017, 460, 127-133.
  • Somatostatin receptor-targeted organometallic iridium(III) complexes as novel theranostic agents, Vojtech Novohradsky, Ana Zamora, Albert Grandioso, Viktor Brabec, Jose Ruiz, Vicente Marchan Chem. Commun. 2017, 53, 5523-5526.
  • New Acridine Thiourea Gold(I) Anticancer Agents: Targeting the Nucleus and Inhibiting Vasculogenic Mimicry, Sergio A. Perez, Concepcion de Haro, Consuelo Vicente, Antonio Donaire, Ana Zamora, Juraj Zajac, Hana Kostrhunova, Viktor Brabec, Delia Bautista, Jose Ruiz ACS Chem. Biol. 2017, 12, 1524-1537.
  • Identification of two frataxin isoforms in Zea mays: Structural and functional studies, Celeste Buchensky, Manuel Sanchez, Martin Carrillo, Oscar Palacios, Merce Capdevila, Jose-M. Dominguez-Vera, Maria V. Busi, Silvia Atrian, Maria A. Pagani, Diego F. Gomez-Casati Biochimie 2017, 140, 34-47.
  • pH-Driven preparation of two related platinum(II) complexes exhibiting distinct cytotoxic properties, Jordi Molas Saborit, Amparo Caubet, Rosa F. Brissos, Luís Korrodi-Gregório, Ricardo Pérez-Tomás, Manuel Martínez and Patrick Gamez Dalton Trans. 2017, 46, 11214-11222.
  • Iron chemistry at the service of life, Manu Sánchez, Laura Sabio, Natividad Gálvez, Merce Capdevila, Jose M. Dominguez-Vera IBUMB Life 2017, 1-7.
  • Highly active group 11 metal complexes with alpha-hydrazidophosphonate ligands, Daniel Salvador-Gil, Lourdes Ortego, Raquel P. Herrera, Isabel Marzo, M. Concepcion Gimeno Dalton Trans. 2017, 46, 13745-13755.
  • Histidine-rich Oligopeptides to Lessen Copper-Mediated Amyloid-β Toxicity, Ana B. Caballero, Laia Terol-Ordaz, Alba Espargaró, Guillem Vázquez, Ernesto Nicolás, Raimon Sabaté, and Patrick Gamez Chem.Eur. J. 2016, 22, 7268-7280.
  • Non-Switching 1,2-Dithienylethene-Based Diplatinum(II) Complex Showing High Cytotoxicity, Andreu Presa, Leoní Barrios, Jordi Cirera, Luís Korrodi-Gregório, Ricardo Pérez-Tomás, Simon J. Teat, and Patrick Gamez Inorg. Chem. 2016, 55, 5356-5364.
  • Bioactive gold(I) complexes with 4-mercaptoproline derivatives, Alejandro Gutiérrez, Carlos Cativiela, Antonio Laguna and M. Concepción Gimeno Dalton Trans. 2016, 45, 13483-13490.
  • Cytotoxicity and biodistribution studies of luminescent Au(I) and Ag(I) N-heterocyclic carbenes. Searching for new biological targets, Renso Visbal, Vanesa Fernández-Moreira, Isabel Marzo, Antonio Laguna and M. Concepción Gimeno Dalton Trans. 2016, 45, 15026-15033.
  • "The Golden Method": Electrochemical Synthesis Is an Efficient Route to Gold Complexes, Luis M. González-Barcia, María J. Romero, Ana M. González Noya, Manuel R. Bermejo, Marcelino Maneiro, Guillermo Zaragoza, and Rosa Pedrido Inorg. Chem. 2016, 55, 7823-7825.
  • An unusual assembled Pb(II) meso-helicate that shows the inert pair effect, María J. Romero, Rocío Carballido, Laura Rodríguez-Silva, Marcelino Maneiro, Guillermo Zaragoza, Ana M. González-Noya and Rosa Pedrido Dalton Trans. 2016, 45, 16162-16165.
  • Highly potent extranuclear-targeted luminescent iridium(III) antitumor agents containing benzimidazole-based ligands with a handle for functionalization, Jyoti Yellol, Sergio A. Pérez, Gorakh Yellol, Juraj Zajac, Antonio Donaire, Gloria Vigueras, Vojtech Novohradsky, Christoph Janiak, Viktor Brabec and José Ruiz Chem. Commun. 2016, 52, 14165-14168.
  • Selectivity of thiosemicarbazonatocopper(II) complex towards duplex RNA. Relevant noncovalent interactions both in solid state and solution, Rubén Gil-García,  María Ugalde, Natalia Busto, Héctor J. Lozano, José M. Leal, Begoña Pérez, Gotzon Madariaga, Maite Insausti, Luis Lezama, Roberto Sanz, Lidia M. Gómez-Sainz, Begoña García and Javier García-Tojal Dalton Trans. 2016, 45, 18704-18718.

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News

1 January 2018: Adoración Gómez-Quiroga becomes the coordinator of the network

 

7 March 2017: Conchita Gimeno is one of the awardees of the IUPAC 2017 Distinguished Women in Chemistry

 

14 october 2015: The Ministry of Economy and Competitiveness of Spain finances the network

Ref: CTQ2015-70371-REDT

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